Clinical Research Fellow Rare Disease Genomics, ICGNMD-2(UK Sponsorship)

Automotive Jobs
Uk
April 25, 2026
Full Time Permanent
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Job Description

About the Department

The Department of Neuromuscular Diseases is internationally recognised for its work in diagnosing, understanding, and treating a wide spectrum of neuromuscular and spinal conditions. Its multidisciplinary teams combine clinical expertise with advanced genetic and laboratory research to uncover disease mechanisms and develop innovative therapies.

Within the department, the Neurogenetics Research Group—led by Professor Henry Houlden—focuses on complex neurological disorders such as ataxias, multiple system atrophy, hereditary spastic paraplegia, and Charcot-Marie-Tooth disease. The group is at the forefront of integrating genomics into clinical practice.

Role Overview

This position offers a unique opportunity to combine clinical practice with cutting-edge genomic research. The successful candidate will lead a research project aimed at identifying genetic causes of inherited neuromuscular disorders using a large and diverse patient cohort.

Alongside research responsibilities, the role includes clinical engagement through patient assessments, multidisciplinary meetings, and participation in specialist clinics. You will contribute to the evaluation of complex cases, particularly those without confirmed genetic diagnoses, and play a role in advancing precision medicine approaches.

There is also the potential to register for a PhD, allowing the research undertaken in this role to contribute to a higher academic qualification and support long-term career development in clinical academia.

Key Responsibilities

  • Conduct genomic research to identify causes of rare neuromuscular diseases
    Analyse and interpret complex genetic data in clinical and research settings
    Participate in specialist clinics, including patient assessment and consent for research
    Collaborate with multidisciplinary teams in clinical and academic environments
    Contribute to ongoing studies, including natural history and therapeutic research
    Present findings at meetings and contribute to academic publications

Candidate Profile

Applicants should demonstrate:

  • Registration as a medical practitioner with a licence to practise in the UK (GMC)
    Clinical experience in neurology or related specialties
    Strong understanding of genetic and genomic principles in inherited diseases
    Knowledge of research governance, including Good Clinical Practice (GCP) and data protection standards
    Experience conducting supervised research and contributing to scientific outputs
    Ability to work collaboratively in clinical and research teams

Desirable attributes include:

  • Experience within the NHS environment
    Familiarity with ACMG guidelines for genetic variant interpretation
    Knowledge of advanced genomic techniques (e.g. long-read sequencing, RNA analysis)
    Experience in clinical audit and research methodology

Training and Development

Visa and Immigration Information

This role is open to international applicants and may be eligible for sponsorship. 

Benefits

The position offers a comprehensive benefits package, including:

Equality, Diversity & Inclusion

The organisation is committed to building a diverse and inclusive workforce. Applications are encouraged from individuals of all backgrounds, especially those currently underrepresented in academic medicine and research.

Additional Information

An honorary clinical contract will be arranged with an NHS Trust, subject to necessary checks. Applicants are encouraged to clearly demonstrate how their experience meets the role criteria within their application.

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