Clinical Research Fellow ICGNMD-2(UK Sponsorship)
Job Description
About the Organisation
The UCL Queen Square Institute of Neurology is internationally recognised for its contributions to neurological research and patient care. Within it, the Department of Neuromuscular Diseases is a major centre dedicated to advancing knowledge and treatment of neuromuscular conditions.
The Centre for Neuromuscular Diseases (CNMD) supports more than 5,000 patients each year through specialised NHS services and plays a leading role in clinical trials and translational research across Europe.
The department works in close partnership with the National Hospital for Neurology and Neurosurgery, bringing together expertise in neurogenetics, neuroimaging, neuropathology, and clinical neuroscience.
A key part of this ecosystem is the International Centre for Genomic Medicine in Neuromuscular Diseases (ICGNMD), which focuses on identifying genetic causes of neuromuscular disorders—particularly in underserved populations. Research activities are closely aligned with the Neurogenetics Research Group led by Professor Henry Houlden.
Role Overview
This Clinical Research Fellowship offers an excellent opportunity for a medically qualified doctor to combine clinical practice with cutting-edge genomic research.
The role is structured with approximately 80% clinical involvement and 20% research, allowing you to engage directly with patients while contributing to scientific discovery.
You will work on identifying genetic factors underlying inherited neuromuscular diseases using a large and diverse patient cohort. The position also offers a pathway toward a PhD and a long-term clinical academic career.
Key Responsibilities
- Recruit and assess patients in specialist neuromuscular clinics
Conduct detailed phenotyping and obtain informed consent
Contribute to multidisciplinary clinical discussions
Participate in ongoing research projects, including natural history and interventional studies
Analyse and interpret genetic data in collaboration with research teams
Present findings at conferences and publish in academic journals
You will be supervised by Dr Enrico Bugiardini and Professor Henry Houlden within a highly collaborative research environment.
Training & Development
- Opportunity to progress toward a PhD
Exposure to international research collaborations
Hands-on experience in genomic medicine and translational research
Mentorship from leading experts in neurogenetics
Eligibility Criteria
Applicants must:
- Hold a medical degree
Have completed CMT/IMT training (or equivalent)
Hold MRCP (or paediatric equivalent)
Be registered with the GMC and licensed to practise in the UK
Demonstrate experience in clinical neurology
Have knowledge of genetic mechanisms of disease
Understand research governance, including GCP and clinical audit processes
You should also be organised, able to work independently, and committed to high standards in both clinical care and research.
Salary & Benefits
- Salary range: £51,140 – £78,670 per annum (including London allowance)
41 days annual leave (inclusive of bank holidays and closure days)
NHS-aligned pension scheme (CARE)
Flexible working options (where possible)
Access to on-site gym and nursery
Enhanced parental leave benefits
Staff wellbeing and support services
Visa & Working in the UK
This role is open to international applicants and qualifies for UK visa sponsorship.
To apply, you will need to:
- Submit an up-to-date CV
Complete the online application form
Provide a supporting statement or cover letter explaining how you meet the criteria
Only required documents will be considered during shortlisting.
Additional Information
- An honorary NHS contract will be arranged (subject to DBS clearance)
The post is funded by Wellcome and the Fidelity Bermuda Foundation
Start date: As soon as possible
Diversity & Inclusion
UCL is committed to fostering an inclusive and equitable workplace. Applications are encouraged from candidates of all backgrounds, especially those underrepresented in academic medicine.
