Research Fellow (Bioinformatician) in genetics of inherited neuromuscular diseases(UK Sponsorship)

Job Description

About the Department

University College London hosts a leading Department of Neuromuscular Diseases, bringing together clinicians, geneticists, and biomedical scientists working at the forefront of neurological research.

The department focuses on understanding the biological and genetic mechanisms underlying neuromuscular disorders, with the ultimate goal of translating discoveries into improved diagnostics and treatments for patients worldwide.

It is closely linked with major research centres including the Queen Square Motor Neuron Disease Centre and the International Centre for Genomic Medicine in Neuromuscular Diseases (ICGNMD), as well as the National Hospital for Neurology and Neurosurgery.

About the Role

This is an exciting opportunity for an experienced Bioinformatician to join the International Centre for Genomic Medicine in Neuromuscular Diseases (ICGNMD).

The role focuses on large-scale genomic research aimed at understanding the global genetic basis of neuromuscular diseases, particularly in underrepresented populations. You will work with complex multi-omics datasets, including short-read sequencing, long-read sequencing, and transcriptomic data.

This position offers the opportunity to develop novel analytical methods and contribute to internationally impactful research that directly supports rare disease diagnosis and patient care.

Key Responsibilities

Bioinformatics & Data Analysis

• Analyse large-scale genomic and transcriptomic datasets
  Develop and apply pipelines for short-read and long-read sequencing data
  Integrate multi-omics datasets to investigate disease mechanisms
  Contribute to method development and novel computational approaches

Research Collaboration

• Work closely with clinical scientists, geneticists, and international collaborators
  Contribute to global datasets and collaborative research initiatives
  Communicate findings clearly to multidisciplinary teams

Scientific Output

• Support preparation of manuscripts and research publications
  Contribute to grant applications and research reporting
  Present findings at academic and scientific meetings

About You

Essential Requirements

• PhD in Bioinformatics, Computational Biology, Genetics, or equivalent experience
  Strong understanding of human genetics and genomic variation
  Experience analysing DNA and RNA sequencing data
  Proficiency in programming (e.g. R, Python, or Bash)
  Experience using High Performance Computing (HPC) systems

Key Skills & Attributes

• Strong analytical and problem-solving skills
  Ability to manage complex datasets and deliver accurate results
  Excellent communication skills for interdisciplinary collaboration
  Strong time management and ability to meet research deadlines
  Ability to work effectively in international, multidisciplinary teams

Visa & Employment Information

This role is open to international applicants and may qualify under UK immigration routes

Recruitment Process

• Applicants will be shortlisted based on CV and supporting statement
  Candidates will complete a bioinformatics-based task during interview
  Results of the exercise will be presented as part of the selection process
  Closing Date: 20 April 2026

Salary & Contract Notes

• Appointment as Research Fellow requires a completed PhD
  If PhD is pending, appointment may initially be as Research Assistant
  Progression to Research Fellow will be confirmed upon PhD completion

Benefits

UCL offers a competitive benefits package including:

• 41 days annual leave (including bank holidays and closure days)
  Additional annual leave purchase options
  Defined benefit pension scheme
  Cycle-to-work and travel support schemes
  Immigration and relocation support (where applicable)
  On-site wellbeing and family-friendly facilities
  Staff assistance and mental health support programmes

Equality, Diversity & Inclusion

University College London is committed to building an inclusive and supportive research environment that values diversity in all forms.

Applications are strongly encouraged from underrepresented groups in science and research, including ethnic minorities, disabled people, LGBTQI+ individuals, and women in senior scientific roles.

Additional Information

The International Centre for Genomic Medicine promotes global collaboration to improve understanding of rare neuromuscular diseases, ensuring that genomic medicine benefits patients across all regions of the world.