Research Technician in Protein Biochemistry(UK Visa Sponsorship available)
Job Description
About the Role
We are seeking a Research Technician in Protein Biochemistry to join a Blood Cancer UK-funded project within the Genome Damage and Stability Centre at the University of Sussex.
This project aims to investigate how tyrosine fusion kinases activate cancer signaling pathways in leukemia and how they are regulated by the HSP90 molecular chaperone system.
Your responsibilities will include:
Large-scale recombinant protein production in support of structural biology studies (X-ray crystallography and cryoEM).
Performing biochemical and biophysical assays to study fusion kinase assembly, activity, and interactions with the chaperone system.
Supporting research into new allosteric approaches to inhibit fusion kinase function.
You will be part of a highly collaborative team in the School of Life Sciences and will have opportunities to further develop technical skills and career experience in a world-leading research environment.
About You
The ideal candidate will have:
A BSc (and preferably MSc) in Structural Biology, Biochemistry, Molecular Biology, or a related discipline.
Hands-on experience with large-scale recombinant protein expression in bacterial or insect cells, and subsequent purification techniques.
Practical skills in biochemical and/or biophysical assays (e.g., protein-protein interactions, enzymatic activity) – desirable but not essential.
You should be motivated, organised, and able to work independently as well as collaboratively in a multidisciplinary research team. Strong communication skills (written and oral) and enthusiasm for contributing to scientific discussions are essential.
About the School of Life Sciences
The School of Life Sciences is one of the largest academic schools at Sussex, undertaking research and teaching across a wide range of disciplines from chemistry and biomedicine to ecology and neuroscience.
The School includes the Genome Damage and Stability Centre, an internationally recognised Centre of Excellence, and is home to the Sussex Drug Discovery Centre. We are proud of our world-leading research reputation, diverse academic community, and commitment to equality, diversity, and inclusion.
The School holds a Silver Athena Swan Award in recognition of its commitment to advancing gender equality in STEMM.
Why Work at Sussex?
A beautiful 150-acre campus next to the South Downs, with excellent transport links (Falmer train station within 5 minutes’ walk).
Sustainable travel options, including cycle-to-work schemes and campus bus routes.
A collaborative, research-led, international university where staff are at the heart of our success.
Find out more about our reward and benefits package and our work on equality, diversity, and inclusion.
Closing date: Monday 29th September 2025, 3:59 PM
Interview date: To be confirmed
Start date: October 2025
Contract length: 6 months (fixed term)
Please include a full CV with your application.
The University welcomes applications from all backgrounds, and particularly encourages applications from women and Black and Minority Ethnic candidates, who are under-represented in STEMM roles.
Visa Sponsorship: This role may be eligible for sponsorship. Please note that ATAS clearance may be required if sponsorship is needed.
