Research Fellow (Mitochondrial Medicine UK visa sponsorship available)
Job Description
About Us
The Department of Clinical and Movement Neurosciences is internationally recognized for research into neurodegenerative disorders. Professors Spinazzola and Holt lead a world-class group in mitochondrial medicine, with pioneering discoveries in mitochondrial DNA (mtDNA) mutations and disease. Their work focuses on translating this knowledge into potential therapies for currently incurable mtDNA disorders, using both cell and animal models.
About the Role
We are recruiting a Research Fellow to join Professors Spinazzola and Holt’s team. The successful candidate will investigate compounds that eliminate harmful mtDNA molecules and explore their potential as treatments for mitochondrial diseases.
Key objectives include:
Assessing the effects of small molecules on key cell types (especially neurons and cardiomyocytes).
Identifying metabolic conditions that support functional mtDNA.
Characterizing molecular events linking mitochondrial dysfunction to disease.
The post-holder will use targeted and omics-based approaches with patient-derived stem cell models and transgenic mice, working as part of a collaborative research team.
This position is funded until 30 April 2027 and is available immediately.
About You
Applicants must hold a PhD or MD in Neuroscience, Developmental Biology, Molecular Biology, or a related field.
Essential expertise includes:
Biochemistry and Molecular Biology
Stem cell-derived models
Application Requirements
Applicants must submit:
A full CV
A one-page research statement explaining suitability for the role and motivation
Names and contact details of three referees
Informal enquiries:
Visa Sponsorship
This role meets eligibility requirements for a Skilled Worker visa or a Global Talent visa. International applicants are welcome.
What We Offer
41 days holiday (27 annual leave, 8 bank holidays, 6 closure days)
Option to purchase up to 5 extra days leave
Defined benefit pension (CARE scheme)
Cycle to work scheme, season ticket loan, immigration loan
On-site nursery and gym
Enhanced maternity, paternity, and adoption pay
Employee Assistance Programme
Discounted medical insurance
Full benefits information: UCL Rewards and Benefits
Equality, Diversity and Inclusion
UCL is committed to being fair, inclusive, and representative of the global community. The Institute holds an Athena SWAN Silver Award and actively supports Equality, Diversity and Inclusion (EDI) initiatives. We particularly welcome applications from groups underrepresented in UCL’s workforce, including Black, Asian and ethnic minority candidates, disabled people, LGBTQI+ and gender diverse people, and women at senior grades.
