Job Description
About the Role
Cardiovascular disease remains the leading global cause of death, with platelets playing a critical role in thrombus formation. This project aims to map the signaling pathways driving platelet and megakaryocyte communication and coordination, combining cutting-edge experimental and computational approaches.
You will use techniques such as:
Advanced microscopy (confocal and intravital)
Flow cytometry
Ex vivo and in vivo thrombus formation models
The project is designed to integrate experimental biology with computational modelling, offering the opportunity to work in a truly multidisciplinary environment.
Responsibilities
Design and conduct assays to study platelet and megakaryocyte signalling, communication, and thrombus formation.
Apply advanced imaging methods to investigate cellular dynamics (e.g., Ca²⁺ signalling).
Collaborate closely with a second PDRA leading the computational side of the project.
Support outreach and dissemination activities, including video blogs and workshops.
Contribute to publications, presentations, and scientific communication within the research community.
About You
You will have:
A PhD (or near completion) in cardiovascular biology, cell biology, or a related field.
Proven experience in fluorescence microscopy for studying cellular processes.
A track record of publications and experience presenting at conferences.
Strong communication and teamwork skills, with the ability to work across disciplines.
Desirable:
Experience with intravital microscopy to study thrombus formation in vivo, or willingness to learn.
Contact Information
Our Commitment
The University of Reading is committed to diversity, equality, and inclusion, and supports:
Athena SWAN Charter for gender equality
Race Equality Charter
LGBT+ equality initiatives
Disability Confident Employer (Level 2)
Applications for job-share, part-time, and flexible working are welcomed.