STRATIFY Lupus Clinical Research Fellow(UK Visa Sponsorship)

Job Description

About the Department

UCL is globally recognised for excellence in biomedical sciences and translational medicine. The successful candidate will join Professor Ehrenstein’s translational research group, which bridges laboratory research with early-phase clinical trials in autoimmune rheumatic diseases.

The group collaborates closely with UCLH, a world-leading centre for systemic lupus erythematosus (SLE) research and patient care. This partnership ensures seamless integration of science and clinical practice, allowing patients to be recruited into both observational and interventional trials.

Key team members include:

• Dr Muhammad Shipa, Principal Investigator and Consultant Rheumatologist
• Research nurses, trial coordinators, and lupus consultants providing multi-disciplinary expertise
• This structure offers an unparalleled environment to gain experience across basic science, translational research, and clinical trials.

About the Role

The STRATIFY-LUPUS trial is the first biomarker-enrichment trial for SLE patients, funded by Arthritis UK and NIHR EME, with recruitment starting May 2026.

Patients eligible for B cell depletion and positive for the serum biomarker IgA2 anti-DNA antibodies will be randomised to either:

• Rituximab alone, or
• Rituximab followed by Belimumab

The post-holder will:

• Lead clinical aspects of trial conduct, focusing on patient recruitment at UCLH
• Liaise with local hospitals to increase referrals for eligible participants
• Collaborate with the UCL Clinical Trial Unit, including trial managers, statisticians, and data managers
• Integrate clinical trial processes with laboratory analyses
• Gain hands-on experience in lupus clinical trials and laboratory research
• Contribute to publications and PhD fellowship applications (if desired)
• Access funding to attend national and international conferences

Flexible arrangements:

• 50% clinical fellow + 50% educational role at UCLH (funding pending)
• Possibility to combine with another UCL/UCLH-funded position
• Eligible for sponsorship and Out-of-Programme Research (OOPR)

Candidate Profile

We are seeking a highly motivated medically qualified clinical fellow (maximum ST4 grade limited by funding) with:

• Medical degree (MBBS or equivalent)
• Active or planned enrollment in a rheumatology training program
• Full GMC registration
• Membership of the Royal College of Physicians
• Completed General Professional Training (or equivalent)
• Experience in rheumatology outpatient clinics and inpatient care for SLE patients

Desirable but not essential:

• Knowledge of clinical trial processes
• Laboratory experience
• The ideal candidate is proactive, detail-oriented, and eager to engage in multidisciplinary translational research.

Appointment Details

• Contract length: 1 year (starting October 2026)
• Flexible options for combining clinical and educational roles

Eligible for sponsorship:

• Skilled Worker visa
• Global Talent visa
• Employer sponsorship guidance
• Right to work in the UK
• Immigration guidance

Benefits

UCL offers a generous package including:

• 41 days holiday (27 annual leave + 8 bank holidays + 6 closure days)
• Additional 5 days leave purchase scheme
• CARE pension scheme (career average revalued earnings)
• Cycle to work and season ticket loan schemes
• Immigration loan and relocation support (where applicable)
• On-site nursery and gym
• Enhanced maternity, paternity, and adoption pay
• Employee Assistance Programme and discounted medical insurance

Equality, Diversity & Inclusion

UCL is committed to fostering diversity and inclusion, ensuring that all staff feel valued and supported. We particularly encourage applications from underrepresented groups, including:

• Black, Asian, and minority ethnic candidates
• Disabled individuals
• LGBTQI+ and gender-diverse applicants

The department holds an Athena SWAN Silver award for its demonstrable commitment to gender equality and inclusive practices. Learn more: UCL Equality, Diversity & Inclusion

How to Apply

Applicants should submit:

• UCL online application form
• Personal statement demonstrating how they meet the essential and desirable criteria
• CV and any supporting documentation