Research Fellow(UK Sponsorship)
Job Description
About the Research Environment
This position sits within a leading research department dedicated to understanding diseases that cause dementia and related neurological decline. The focus is on uncovering how genetic, cellular, and molecular processes contribute to neurodegeneration.
You will collaborate across two well-established labs:
Isaacs Lab: Focuses on frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), especially genetic causes like C9orf72 and CHMP2B.
Niccoli Lab (Institute of Healthy Ageing): Investigates how and why neurons die in conditions such as Alzheimer’s disease and ALS/FTD, using fruit fly (Drosophila) models.
About the Role
This post builds on recent findings showing that certain fatty acids may protect neurons in models of FTD and ALS. Your work will explore how this protection happens at a molecular level using Drosophila systems.
You will:
Design and run experiments to investigate neurodegeneration mechanisms
Work closely with senior researchers while gradually becoming independent
Contribute to experimental planning, data analysis, and scientific discussions
Be part of a collaborative and supportive research team
Candidate Profile
You should have (or be close to completing):
A PhD in biomedical sciences or a related field
Strong understanding of genetics and molecular biology
Experience with techniques such as qPCR
Hands-on experience with genetic crosses
Desirable skills include:
Working with Drosophila models
Microscopy, immunostaining, and image analysis
A strong interest in neuroscience and neurodegenerative diseases is essential.
Salary & Benefits
- £45,103 – £49,943 per year (including London allowance)
If PhD not yet awarded: initial appointment at Research Assistant level (£39,148 – £41,833)
41 days annual leave (including holidays and closure days)
Defined benefit pension scheme
Family-friendly policies and enhanced parental leave
On-site facilities (gym, nursery)
Cycle-to-work and travel loan schemes
Immigration support options
Visa & Eligibility
This role qualifies for UK visa sponsorship. You may be eligible under routes such as:
Global Talent visa (research route)
Additional Support for Applicants
Guidance on working in the UK
Employee rights and workplace conditions
Equality and workplace protections
Why Apply?
This is an excellent opportunity to work on cutting-edge neurodegeneration research with real clinical relevance. You’ll gain experience in advanced disease modelling, collaborate with leading scientists, and contribute to discoveries that may shape future therapies for dementia and ALS.
