Job Description
About the Research Environment
The Alzheimer’s Research UK Drug Discovery Institute at UCL (ARUK UDDI), part of University College London, is dedicated to transforming early-stage scientific discoveries into therapies for neurodegenerative diseases.
As a key member of the Dementia Discovery Alliance, the institute collaborates with leading centres in Oxford and Cambridge to accelerate the development of treatments for conditions such as Alzheimer’s disease.
Positioned within the UCL Institute of Neurology, the institute benefits from:
- A strong translational research ecosystem
Integration of biology, chemistry, and pharmacology expertise
Access to advanced laboratory technologies and analytical platforms
About the Role
This role offers an opportunity to contribute directly to innovative drug discovery programmes. As a Research Fellow or Senior Research Fellow, you will lead and support biological research across the drug development pipeline.
Your work will involve:
- Designing and delivering in vitro and in vivo studies
Supporting target identification, validation, and proof-of-concept research
Generating and interpreting biological data to guide decision-making
Collaborating across multidisciplinary teams and external partners
You will also contribute to integrating a wide range of experimental approaches, including:
- Immunohistochemistry and confocal microscopy
Protein analysis (e.g. Western blotting and automated systems)
RNA-based assays and biomarker studies
Multi-omics approaches such as transcriptomics and proteomics
This is a highly collaborative position with strong links to both academic and industry-facing research environments.
Candidate Profile
Essential Requirements
- A PhD in neurobiology or a closely related field
Experience in cellular and molecular biology techniques
Expertise in designing and conducting in vivo studies
Ability to develop and implement assays addressing complex biological questions
Strong communication and teamwork skills
Additional Requirements (Senior Level)
Applicants for the Senior Research Fellow position should also demonstrate:
- Postdoctoral or industry experience in drug discovery
Leadership in in vivo research programmes
Advanced expertise in neurodegeneration research
Proven ability to manage collaborative projects, including external partnerships (e.g. CROs)
Career Development
This role provides an excellent platform to:
- Contribute to translational research with real-world therapeutic impact
Work alongside leading experts in neuroscience and drug discovery
Develop leadership and project management skills
Gain exposure to multidisciplinary and industry-linked research
Salary & Benefits
Salary will be offered based on experience:
- Research Fellow (Grade 7): £45,103 – £52,586
Senior Research Fellow (Grade 8): £54,931 – £64,644
Research Assistant (if PhD pending): £39,148 – £41,833
UCL offers a comprehensive benefits package, including:
- 41 days annual leave (inclusive of bank holidays and closure days)
Option to purchase additional leave
Defined benefit pension scheme (CARE)
Travel support schemes and cycle-to-work programme
Immigration loan assistance
On-site childcare and fitness facilities
Enhanced family leave policies
Staff wellbeing and support services
Visa Sponsorship
This role qualifies for sponsorship under the Skilled Worker visa and may also be eligible under the Global Talent visa route. Applications from international candidates are encouraged.
Application Process
To apply, please submit:
- A current CV
A supporting statement or cover letter demonstrating how you meet the role criteria
For informal discussions: Professor David Chambers
Equality, Diversity & Inclusion
The institute is committed to fostering a supportive and inclusive workplace where all individuals can thrive.
- Athena SWAN Gold Award holder
Active engagement in equality, diversity, and inclusion initiatives
Strong commitment to fair recruitment and career development
Applications are particularly welcomed from individuals who are underrepresented in academic research environments.
Why Join This Role?
This is an opportunity to be part of a mission-driven research institute focused on tackling one of the most urgent challenges in global health. You will contribute to meaningful scientific progress while developing your career in a collaborative and forward-thinking environment.