Research Fellow(UK Sponsorship)

Job Description

About the Role

An exciting opportunity is available for a Research Fellow to join the research group of Dr Leandro Castellano at the University of Sussex. The role focuses on investigating miRNA–mRNA regulatory networks as potential therapeutic targets for immunotherapy in triple-negative breast cancer.

You will lead and conduct independent research, designing and delivering experimental studies to generate high-quality, reproducible data. Your work will contribute to peer-reviewed publications, future grant applications, and presentations at national and international scientific conferences.

Key responsibilities include:

• Designing and executing molecular and cellular biology experiments
  Analysing and interpreting experimental data
  Contributing to publications and funding proposals
  Presenting findings at seminars and conferences
  Supervising undergraduate and postgraduate research students
  Supporting teaching, outreach, and wider academic activities

The role operates within UK research governance frameworks, including:

• Good clinical and research practice
  Data protection (UK GDPR)
  Health and safety in laboratories

You will work in a highly collaborative environment, with access to leading facilities such as the Sussex RNA Research Centre and the Sussex Cancer Research Centre.

About You

You will have a strong background in molecular biology, with a keen interest in cancer biology and immunology. You will contribute to identifying and characterising novel miRNAs involved in tumour immune evasion.

Essential skills and experience include:

Experience with CRISPR-based genome editing
Cell culture and manipulation of cancer cell lines
Laboratory techniques such as flow cytometry, immunoblotting, RT–qPCR, and RNA immunoprecipitation
Strong data analysis and problem-solving skills
Ability to work both independently and collaboratively

Experience in RNA biology, cancer research, or immunological assays is desirable. A proactive approach and strong communication skills are essential.

You should also be familiar with relevant UK research and ethical standards, such as:

• Use of animals in research (if applicable)
  Ethical approval processes
  Scientific research funding guidance

About the School

The School of Life Sciences at the University of Sussex is internationally recognised for its research excellence across disciplines including molecular biosciences, neuroscience, chemistry, and ecology.

The School hosts world-leading research centres such as the Genome Damage and Stability Centre and Sussex Neuroscience, alongside a strong research portfolio exceeding £50 million.

The School is committed to fostering a collaborative, inclusive, and supportive environment, guided by values of integrity, diversity, and innovation. It proudly holds a Silver Athena Swan Award for its commitment to equality and inclusion.

Why Work at Sussex

The University of Sussex offers a dynamic and inclusive workplace located near the South Downs National Park.

Benefits include:

• Excellent transport links (Falmer station within walking distance)
  Cycle-to-work scheme
  Strong research culture and career development opportunities
  Commitment to equality, diversity, and inclusion

Eligibility & Visa Sponsorship

This role meets the requirements for Skilled Worker visa sponsorship, subject to eligibility criteria.

Relevant guidance includes:

• Skilled Worker visa overview
  Eligibility criteria
  ATAS clearance (if applicable)

All work must be undertaken within the UK in accordance with immigration regulations.

Additional Information

The University is committed to equality, diversity, and inclusion. Applications from underrepresented groups in STEMM are particularly encouraged.